The Inspired Therapeutics Neomate MCS System for Neonates and Infants
In May 2022, scientists from the University of Louisville (Departments of Cardiovascular and Thoracic Surgery, Bioengineering, Anesthesiology, and Perioperative Medicine), Veritium research LLC, and Inspired Therapeutics LLC tested the NeoMate mechanical circulatory support (MCS) system for neonates and infants. The complete manuscript by Gretel Monreal, Steven C. Koenig, Mark S. Slaughter, Gino F. Morello, Steven R. Prina, Landon H. Tompkins, Jiapeng Huang, Barry N. Gellman, and Kurt A. Dasse can be found in Plos One. Their research is summarized below.
Up to 14,000 US children are hospitalized yearly with heart failure (HF)-related conditions. These children show a mortality rate of 7-15%, while the mortality rate of those on the waiting list for a heart transplant ranges from 5-39%. Because of these statistics, temporary and durable mechanical circulatory support devices prove to be important in supporting this patient population.