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Medical Perfusion
Industry News

Ethical Implications of Discontinuing ECMO in Children with Irreversible Cardiorespiratory Failure

In January 2024, researchers from Harvard Medical School (Department of Pediatrics), Boston Children’s Hospital (Department of Cardiology and Office of Ethics), Children’s Hospital at Westmead Clinical School (Clinical and Population Translational Health), MaineGeneral Medical Center (Department of Pediatrics), Perelman School of Medicine at the University of Pennsylvania (Department of Anesthesiology and Critical Care), and the…


Blood: A Historical and Cultural Background

In the annals of history, the concept of blood has transcended its physiological role, assuming a myriad of cultural and symbolic meanings in the Old World. This vital fluid has been woven into the fabric of religious practices, rituals, and societal beliefs, reflecting ancient cultures’ diverse perspectives and values.In the realm of ancient Egypt, blood…


Mental Health and well-being Tools for Health Care Workers

Mental health is a crucial aspect of overall well-being, and healthcare workers, like anyone else, can face unique challenges in maintaining good mental health. The demanding nature of their jobs, long hours, exposure to trauma, and the pressure to provide high-quality care can contribute to stress and burnout. Working in a high-stress clinical setting is…


Cost of Permanent Pacemaker Implantation in Pediatric Patients with Postoperative Heart Block

In November 2023, researchers from Boston Children’s Hospital (Department of Cardiac Surgery and Department of Cardiology), Harvard Medical School (Department of Surgery and Department of Pediatrics), and University of Utah (Division of Epidemiology and Department of Biomedical Engineering) estimated the economic burden to patients and their families following permanent pacemaker (PPM) implantation. The complete manuscript…


Applications of Electrosurgery in Interventional Cardiology

In January 2023, researchers from the National Heart Lung and Blood Institute (Cardiovascular Branch), MedStar Washington Hospital Center, and Emory University Hospital (Structural Heart and Valve Center) investigated typical applications of electrosurgery, including the evidence and key technical steps for each. The complete manuscript by Jaffar M. Khan, Toby Rogers, Adam B. Greenbaum, Vasilis C….


The effect of cardiopulmonary bypass on blood thiamine concentration and its association with postoperative lactate concentration

There is a relationship between thiamine levels and hyperlactatemia following cardiothoracic surgery. Hyperlactatemia is commonly seen in these patients and is associated with higher morbidity and mortality rates. Lactate gets produced when anaerobic metabolism occurs, boosting its concentrations and reducing thiamine levels. Thiamine is essential for aerobic metabolism, as it is necessary for the enzyme…


Long-Term Outcomes and Durability of Transcatheter Aortic Valve Implantation

In May 2023, researchers from Loyola University Medical Center and Houston Methodist DeBakey Heart & Vascular Center discussed the mid-to-long-term clinical outcomes observed in landmark transcatheter aortic valve implementation (TAVI) trials. They analyzed the long-term durability of transcatheter heart valves (THVs). The complete manuscript by Parth V. Desai, Sachin S. Goel, Neal S. Kleiman, and…


Gaseous Micro-Embolic Activity and Goal-Directed Perfusion Management in a Closed System for Cardiopulmonary Bypass and Minimally Invasive Extracorporeal Circulation during Coronary Artery Bypass Grafting.

The world of extracorporeal technologies is rapidly expanding. In particular, we are trying to make cardiopulmonary bypass (CPB) more physiological for end-organ protection by reducing complications related to biocompatibility, inflammation, hemodilution, coagulation management, and gaseous micro-embolic activity. The literature describes various extracorporeal techniques that seek to eliminate air-blood contact and reduce hemodilution and the contact…


The Role of The Alternative Pathway in Complement Activation by HIT Immune Complexes

 Researchers from Duke University Medical Center (Division of Hematology), Children’s Hospital of Philadelphia, Perelman University of Pennsylvania School of Medicine (Department of Pathology and Laboratory Medicine and Medicine), Texas A&M University (Department of Microbial Pathogenesis & Immunology), and East Carolina University (Department of Microbiology & Immunology examined how the alternative pathway contributes to complement activation…


 ECMO: A bridge to Patient Care

ECMO (Extracorporeal Membrane Oxygenation) has dramatically evolved since its introduction in the 1960s with Dr. Gibbon’s first version of a heart-lung machine to Dr. Robert Bartlett’s first neonatal survivor in 1974 to the process we now experience. Since 1989, over 204,000 ECMO cases have been submitted to ELSO (Extracorporeal Life Support Organization). Although most ECMO…


How Do We Forecast Tomorrow’s Transfusion: Infectious Safety?

Transfusion medicine is constantly evolving, and Pathogen Reduction Technologies (PRTs) are at the forefront, offering distinct advantages and challenges. PRTs aim to minimize the risk of infections transmitted through transfusion while addressing immune responses associated with blood product transfusion. However, the efficacy of PRT-treated blood products can be compromised, potentially escalating the demand for blood…


How can the healthcare system deliver sustainable performance? A scoping review

This scoping review aims to understand how the literature defines, conceptualizes, and measures the sustainable performance of healthcare systems (SPHS). The research was conducted on peer-reviewed articles and editorials published up to February 2021. The study focused on five aspects of SPHS – definitions, measurement, challenges, possible solutions, and the scaling of these solutions. The…


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