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05Jul

Successful Coronary Artery Bypass Grafting in A Patient with Situs Inversus Totalis

In March 2022, a research team from Gunma University detailed the treatment of CABG in situs inversus totalis, a rare anomaly that has been minimally reported in the literature. The complete manuscript by Atsushi Oi, Wataru Tatsuishi, Jun Mohara, Toshikuni Yamamoto, and Tomonobu Abe was published in the Journal of Cardiothoracic Surgery. The case report is detailed below.

Dextrocardia with situs inversus totalis is a congenital anomaly where the organs are mirrored in relation to their typical locations. It is a rare condition, occurring in only 1:10,000 people, and as such, it has been minimally documented.

01Jul

Endovascular Embolization as a Treatment for Subdural hematoma in LVAD Patients

In March 2022, practitioners from the Department of Neurosurgery at Georgetown University School of Medicine described a case study of a 63-year-old female with a preexisting LVAD who received treatment for a chronic subdural hematoma. Below we have summarized the findings from the case report, with the entire manuscript, written by Gnel Pivazyan, Mitchell B. Rock, Ehsan Dowlati, Jeffrey C. Mai, and Robert B. Mason, published in Brain Circulation.

Left ventricular assist devices (LVADs) play an essential role in those with heart failure by providing mechanical circulatory augmentation. However, a unique challenge for those with LVADs is chronic subdural hematomas (cSDH), a type of intracranial hemorrhage, which requires the patient to take continuous anticoagulation medication due to the high risk of thrombotic events.

16Jun

Best Practice Recommendations for Optimizing Care in Structural Heart Programs Using PEARLS

In light of the impact of the COVID-19 pandemic, researchers from coast to coast worked together to offer recommendations for best practices in Planning Efficient and Resource Leveraging Systems (PEARLS) in structural heart programs. The entire manuscript was written by Elizabeth M. Perpetua, Kimberly A. Guibone, Patricia A. Keegan, Roseann Palmer, Martina K. Speight, Kornelija Jagnic, Joan Michaels, Rosemarie A. Nguyen, Emily S. Pickett, Dianna Ramsey, Susan J. Schnell, Shing-Chiu Wong, and Mark Reisman and published in May 2021, can be found in Structural Heart. A summary of their best practice recommendations is outlined below.The COVID-19 pandemic has created an opportunity to refine patient care for structural heart disease (SHD). This evolves around optimal care, informally defined as “the right care for the right patient at the right place at the right time.” A patient’s treatment plan revolves around patient goals and preferences while also weighing risk versus benefit analysis. Additionally recommended when determining a treatment plan are a systemic assessment of Heart Team roles and functions, hospital capacity, and patient and procedural risks that can occur when more resources are used.

05Jun

Renal Hemodynamics And Oxygenation in Critically Ill Patients and After Major Surgery

In May 2021, researchers from the University of Gothenburg Department of Anesthesiology and Intensive Care Medicine took an in-depth analysis of the health status of those with acute renal dysfunction due to health conditions such as early clinical septic shock, chronic renal failure, postoperative AKI, liver transplantation, and cardiac surgery with cardiopulmonary bypass. The complete manuscript, written by Sven-Erik Rickstein, Gudrun Bragadottir, Lukas Lannemyr, Bengt Redfors, and Jenny Skytte, can be found on the Kidney 360 website. The results of the study are detailed below.

The primary data set obtained by this study was renal oxygen, with its availability determined by the balance of renal oxygen delivery (RDO2) and renal oxygen consumption (RVO2). The results were then separated by the health condition contributing to acute renal dysfunction, with the following key findings.

Rickstein et al. first measured renal perfusion, filtration, and oxygenation in patients within 24-hours of hospital admittance due to early clinical septic shock. The results concluded that RDO2 was impaired in these patients due to renal vasoconstriction and the redistribution of blood flow away from the kidneys.

31May

Uncovering Hot Topics in Healthcare Operations and Supply Chain Management

In March 2022, Imran Ali and Devika Kannan released a paper that sought to advance the body of knowledge surrounding healthcare operations and supply chain management through a literature review. The full manuscript by Ali et al. can be found in the Annals of Operations Research. The result of the literature review is detailed below.

The key to counteracting emergent diseases (such as the COVID-19 outbreak) and promoting the health and well-being of patients lies in the effective and efficient delivery of healthcare services. With the onset of the COVID-19 pandemic, the literature surrounding healthcare operations and supply chain management has seen immense growth. However, previous literature reviews possessed varying scopes and emphases focused on a specific topic.

22May

Variations in Information Reported Amongst Studies Regarding Coagulation in Pediatric ECMO

A study published in March assessed how outcome definitions, study population, and ECMO-, transfusion-, and coagulation- related parameters were described in pediatric ECMO studies. The complete manuscript was written by Joppe Drop, Suelyn Van Den Helm, Paul Monagle, Enno Wildschut, Matthijs de Hoog, Sabrina T.G. Gunput, Fiona Newall, Heidi J. Dalton, Graeme MacLaren, Vera Ignjatovic, and C. Heleen van Ommen. It can be found in Research and Practice in Thrombosis and Haemostasis. The significant findings are detailed below.

Extracorporeal membrane oxygenation (ECMO) is often used in children with severe refractory cardiac or pulmonary failure and has dramatically increased use with pediatric patients. Despite this, cases with hemostatic complications such as thrombosis and bleeding remain high in children. The purpose of the reported systemic review was to form a foundation for a standardized ECMO framework by assessing how ECMO-related parameters and complications were described within existing studies.

21Apr

Mechanical ventilation, prone positioning, and delivery in pregnant patients with severe COVID-19

In February, practitioners from the University of Maryland Department of Anesthesiology published a study on the care and outcomes of 17 pregnant COVID-19 patients who required mechanical ventilation. The full manuscript, written by Michael Wong, Shobana Bharadwaj, Allison Lankford, Jessica Galey, and Bhavani Kodali, is available on the Journal of Obstetric Anesthesia website.

18Apr

Role of circulating Interleukin-7 (IL-7) and its inverse correlation with Pulmonary arterial hypertension

The team at the pediatric cardiology and critical care department at Hanover medical school in Germany, including Franziska Diekmann, Ekaterina Legchenko, Philippe Chouvarine, Ralf Lichtinghagen, Harald Bertram, Christoph M. Happel, and Georg Hansmann, recently published a study investigating the role of circulating Interleukin-7(IL-7) and its inverse correlation with the Pulmonary arterial hypertension (PAH) in humans. However, the exact mechanism of IL-7 on the severity of PAH is still unknown.

16Apr

Pigmentation Affects Elastic Fiber Patterning and Biomechanical Behavior of the Murine Aortic Valve

Sana Nasim, Popular Pandey, Rosemerie M. Kanashiro-Takeuchi, Jin He, Joshua D. Hutcheson, and Lisi Kos recently published a paper looking at the relationship between aortic valve pigmentation and elasticity, building on their previously-published work. Their full manuscript is publicly available in Frontiers in Cardiovascular Medicine. Here, we summarize their findings.

09Apr

Study Explores Size Ratio in Aortic Valve Leaflets and Root Using CT Imaging

This is a summary of the study conducted by Tianyang Yang, Haini Wen, Ismail El-Hamamsy, Qiming Ni, Yanbin Sun, and Dan Zhu available to read here entitled “Relationship Between Leaflets and Root in Normal Aortic Valve Based on Computed Tomography Imaging: Implication for Aortic Valve Repair” published in Frontiers in Cardiovascular Medicine in November 2021.