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A Sneak-Peek into the Physician’s Brain: Weighing TAVR vs. SAVR for Aortic Stenosis Treatment

In the contemporary era, for the treatment of severe symptomatic aortic stenosis, transcatheter aortic valve replacement (TAVR) has become a viable alternative to isolated surgical aortic valve replacement (iSAVR). The evolution of TAVR over the previous two decades, particularly its usage in younger patients, has provided a glimpse of the new technique's progressive integration into everyday practice.


Non-Invasive Biomarkers of Fontan Associated Liver Disease

Surgical palliation (resulting in the Fontan circulation and total cavo-pulmonary connection) is beneficial to palliate symptoms in patients with a range of congenital cardiac diseases and lesions as hypoplastic left heart syndrome and tricuspid atresia. Passive venous flow directly enters the pulmonary circulation, increasing oxygen saturation in arterial blood.


Cardiac Structural Remodeling and Hemodynamic Patterns Following Transcatheter Aortic Valve Replacement

The PARTNER (Placement of Aortic Transcatheter Valve Trial) has been paving the way since 2011, establishing that transcatheter aortic valve replacement (TAVR) is equally effective as surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis (AS) who are at high surgical risk. In 2019, the advantages of TAVR were extended to patients with minimal surgical risk, with decreased rates of mortality, stroke, and re-hospitalization after one year than with SAVR.


Use of Intraoperative Blood Autotransfusion in Obstetrics

During pregnancy, maternal hemorrhage is a significant risk. It could cause maternal morbidity and mortality. Intraoperative cell salvage is becoming more common in obstetric surgery worldwide for women who are at risk of peripartum hemorrhage after cesarean delivery. It includes a collection of the patient's blood from the surgical field, cleansing away the contaminants, and re-infuse it to the patient, avoiding the dangers and expenses of allogeneic transfusion.


Cardioplegia from Depolarized to Polarized Cardiac Arrest in Adult Cardiac Surgery

For a long time, wounds of the heart have been untreatable and fatal. The first cardiac wound was healed in the USA by St. Louis in 1891. In 1923, the first surgery (closed-heart surgery) was performed by Levine and Cutler in Boston, which also helped treat mitral stenosis via commissurotomy. After 35 years, open-heart surgery came into place with different health challenges, precautions, and red flags.


Advantages and Disadvantages in Anticoagulation and Coating Methods Used in Extracorporeal Life Support Devices

In the previous few decades, the usage of extracorporeal life support (ECLS) technologies has skyrocketed. Despite medical and scientific breakthroughs, the intricate interplay between the human body, blood, and artificial materials remains a major problem in the ECLS sector. Blood exposure to artificial surfaces does cause an imbalanced activation of the coagulation cascade, which can result in hemorrhagic and thrombotic events.