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Variations in Information Reported Amongst Studies Regarding Coagulation in Pediatric ECMO

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A study published in March assessed how outcome definitions, study population, and ECMO-, transfusion-, and coagulation- related parameters were described in pediatric ECMO studies. The complete manuscript was written by Joppe Drop, Suelyn Van Den Helm, Paul Monagle, Enno Wildschut, Matthijs de Hoog, Sabrina T.G. Gunput, Fiona Newall, Heidi J. Dalton, Graeme MacLaren, Vera Ignjatovic, and C. Heleen van Ommen. It can be found in Research and Practice in Thrombosis and Haemostasis. The significant findings are detailed below.

Extracorporeal membrane oxygenation (ECMO) is often used in children with severe refractory cardiac or pulmonary failure and has dramatically increased use with pediatric patients. Despite this, cases with hemostatic complications such as thrombosis and bleeding remain high in children. The purpose of the reported systemic review was to form a foundation for a standardized ECMO framework by assessing how ECMO-related parameters and complications were described within existing studies.