A groundbreaking study recently published in the Extracorporeal Life Support Organization (ELSO) Registry by Andrew Kalra and colleagues has made significant progress in the prediction of acute brain injury (ABI) in patients undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) or extracorporeal cardiopulmonary resuscitation (ECPR). By leveraging sophisticated tree-based machine learning algorithms such as Random Forest, CatBoost, LightGBM,…