Tianyu Zhang and colleagues recently published a systematic review and meta-analysis in Frontiers in Medicine evaluating reduced-intensity and heparin-sparing anticoagulation strategies during Extracorporeal Membrane Oxygenation (ECMO). Systemic anticoagulation with unfractionated heparin has traditionally represented the standard of care in ECMO management; however, bleeding complications continue to pose a significant challenge. The study aimed to determine…