Nafis M. Arefin and Bryan C. Good examined the impact of arterial cannula orientation on hemodynamics during cardiopulmonary bypass (CPB) using patient-specific computational fluid dynamics (CFD). Four anatomically distinct ascending aortic models: pediatric, adolescent, adult, and geriatric, were reconstructed from imaging data to compare the conventional 90° (perpendicular) cannulation technique with a 30° angled approach….