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Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors

Cho Yeow Koh and colleagues recently published an article on the efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors in Nature Communications. Here we summarize their work, which is also publicly available on Nature.com. Procedures like percutaneous coronary intervention (PCI) increase thrombin generation that results in clotting, which must be combatted using anticoagulants. Common…

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