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Optimizing CO₂ Levels in Acute Brain Injury: Balancing Cerebral Blood Flow and Intracranial Pressure

The article “Carbon dioxide pathophysiology and targets following acute brain injury” by Shaurya Taran et al., published in Intensive Care Medicine, highlights the crucial role of arterial carbon dioxide tension (PaCO₂) in the management of acute brain injury (ABI). PaCO₂ strongly influences cerebral blood flow (CBF): higher levels cause vasodilation and increased CBF, while lower…

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